G005712

LC/MS Analysis of Omeprazole and Metabolites on Ascentis^® Express RP Amide (pH 3.4)

application for HPLC

속성

• 기술: HPLC: suitable
• 검사 파라미터: column: Ascentis Express RP-Amide, 5 cm x 2.1 mm I.D., 2.7 μm particles (53911-U); mobile phase: [A] 10 mM ammonium formate in water, pH 3.4; [B] 10 mM ammonium formate in methanol, pH 3.4; (65:35, A:B); flow rate: 0.3 mL/min; column temp.: 35 °C; detector: ESI(+), m/z 50-400; injection: 1 μL; sample: 1 mg/L in mobile phase
• 적합성: application for HPLC
• 응용 분야: clinical

설명

분석 메모

This application demonstrates the suitability of the Ascentis Express RP Amide for the analysis of omeprazole metabolites.

법적 정보

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

분석물

5-Hydroxyomeprazole
Omeprazole
Omeprazole sulfone