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58151AST

CHIRALPAK® AGP (5 μm) HPLC Columns

L × I.D. 15 cm × 4 mm, HPLC Column

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1 EA
₩8,564,875

₩8,564,875

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1 EA
₩8,564,875

About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

₩8,564,875

구입 가능 여부는 고객센터에 문의하십시오.

제품명

CHIRALPAK® AGP HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4 mm

material

stainless steel column

Quality Level

100

Agency

suitable for USP L41

제품 라인

CHIRALPAK®

포장

pkg of 1 ea

제조업체/상표

CHIRALPAK®

파라미터

137 bar pressure (2000 psi)
20-30 °C temperature
40 °C max. temp.

기술

HPLC: suitable

길이 × I.D.

15 cm × 4 mm

Matrix

fully porous particle

기질 활성군

glycoprotein, alpha1- phase

입자 크기

5 μm

작동 pH

2-8

분리 기술

chiral

저장 온도

2-8°C

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일반 설명

Hermansson described the use of natural proteins immobilized onto a silica support for chiral separations in 1983 (1). Proteins contain a large number of chiral centers of one configuration, and many other sites that contribute to the general retention process. CHIRALPAK AGP has the broadest range of selectivity of all protein phases currently available. CHIRALPAK AGP phase uses α1-acid glycoprotein (AGP) as the chiral selector immobilized on spherical 5 μm silica particles. Bonded AGP is a very stable protein that tolerates pure organic solvents, elevated temperatures and pH values from 4 to 7. Operated in reversed-phase mode, CHIRALPAK AGP column separates enantiomers of an extremely broad range of drug substances, such as acids, amines and neutral compounds. The enantioselectivity and retention can easily be regulated by mobile phase pH and ionic strength, and the nature and concentration of the organic modifier.

Features:
  • Direct reversed phase resolution of chiral molecules
  • Stable with a variety of organic modifiers
  • Available in analytical and semi-preparative sizes

(1) Hermansson, J. Direct liquid chromatographic resolution of racemic drugs using a1-acid glycoprotein as the chiral stationary phase. J. Chromatogr. A, 1983, 269, 71-80.

애플리케이션


  • Evaluation of R- (-) and S- (+) Clenbuterol enantiomers during a doping cycle or continuous ingestion of contaminated meat using chiral liquid chromatography by LC-TQ-MS: This study demonstrates the use of a chiral HPLC column for the separation of clenbuterol enantiomers in biological samples, providing insights into the detection of doping substances or exposure to contaminated meat (Dolores et al., 2019).

  • Stereochemical characterization of fluorinated 2-(phenanthren-1-yl)propionic acids by enantioselective high performance liquid chromatography analysis and electronic circular dichroism detection: This research highlights the capability of chiral HPLC columns to differentiate between the enantiomers of complex fluorinated compounds, offering a method for detailed analysis crucial in pharmaceutical studies (Bertucci et al., 2012).

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

CHIRALPAK is a registered trademark of Daicel Corp.

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시험 성적서(COA)

Lot/Batch Number

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 답변

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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