추천 제품
제품명
SUPELCOSIL™ ABZ+Plus HPLC Column, 3 μm particle size, L × I.D. 10 cm × 2.1 mm
Agency
suitable for USP L60
특징
endcapped
제조업체/상표
SUPELCOSIL™
라벨링 범위
12.0% carbon loading
파라미터
≤70 °C temp. range
400 bar pressure (5801 psi)
기술
HPLC: suitable
길이 × I.D.
10 cm × 2.1 mm
표면적
170 m2/g
표면 범위
surface coverage 3.4 μmol/m2
Matrix
silica gel, spherical particle platform
기질 활성군
amide, alkyl phase
입자 크기
3 μm
공극 크기
120 Å
pH 범위
2-7.5
응용 분야
food and beverages
분리 기술
reversed phase
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일반 설명
SUPELCOSIL ABZ+Plus columns offer both high deactivation and unique selectivity. Deactivated silica particles of very narrow particle size distribution ensure high efficiency with low back pressure. After bonding and endcapping reactions, the ABZ+Plus phase effectively shields unreacted silanol groups on the silica, preventing them from interacting with most analytes, and provides symmetric peaks regardless of an analyte′s functionality. The phase also allows you to use low ionic strength buffers without having to add an ion-suppressing modifier. ABZ+Plus enables you to use simple mobile phases when analyzing the most difficult compounds; acids, strongly basic compounds, and zwitterions.
suitable for L60 per USP
suitable for L60 per USP
특징 및 장점
• High efficiency for polar, nonpolar, and charged analytes
• Symmetric peaks for the most reactive compounds
• Unique selectivity for polar and charged compounds
• Symmetric peaks for the most reactive compounds
• Unique selectivity for polar and charged compounds
법적 정보
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Zhongping John Lin et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 757-762 (2005-03-31)
A highly sensitive method was developed and validated for determining the free fraction of flunarizine in human plasma. Equilibrium dialysis was used for the separation of free (unbound) drug and liquid chromatography/tandem mass spectrometry (LC-MS/MS) was used for quantitation. Post-dialysis
Tânia M G Almeida et al.
Chemistry & biodiversity, 2(12), 1691-1700 (2006-12-29)
Absorption, distribution, metabolism, and excretion (ADME) properties are of invaluable importance to a bioactive compound. Permeation process is one of the most widely studied by many different techniques. Among them, reversed-phase liquid chromatography (RP-LC) is proving to be of great
Nasser E Bastani et al.
Rapid communications in mass spectrometry : RCM, 23(18), 2885-2890 (2009-08-12)
F2-isoprostanes are a family of prostaglandin F2-like compounds that are formed by free-radical-catalyzed peroxidation of arachidonic acid. Several F2-isoprostanes, but in particular 8-epi PGF(2alpha), are widely used as oxidative stress biomarkers. An analytical method based on liquid chromatography with negative
P Chaimbault et al.
Journal of chromatography. A, 855(1), 191-202 (1999-10-09)
A qualitative determination of 20 underivatized proteinic amino acids by LC-MS is reported. The need for chromatographic separation before mass spectrometry determination is demonstrated based on the study of several amino acid pairs which have some similar characteristics. Two suitable
W Pan et al.
Journal of chromatography. B, Biomedical sciences and applications, 703(1-2), 129-138 (1998-02-03)
A sensitive, specific and precise HPLC-UV assay was developed to quantitate cocaine (COC) and its metabolites benzoylecgonine (BE), norcocaine (NC) and cocaethylene (CE) in rat plasma. After adding 50 microl of the internal standard solution (bupivacaine, 8 microg/ml) and 500
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