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추천 제품
제품명
Discovery® HS C18 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 10 mm
material
stainless steel column
Quality Level
Agency
suitable for USP L1
제품 라인
Discovery®
특징
endcapped
제조업체/상표
Discovery®
포장
1 ea of
라벨링 범위
20% Carbon loading
파라미터
≤70 °C temp. range
400 bar pressure (5801 psi)
기술
HPLC: suitable
길이 × I.D.
25 cm × 10 mm
표면적
300 m2/g
표면 범위
3.2 μmol/m2
불순물
<10 ppm metals
Matrix
silica gel, high purity, spherical particle platform
fully porous particle
기질 활성군
C18 (octadecyl) phase
입자 크기
5 μm
공극 크기
120 Å
작동 pH 범위
2-8
응용 분야
food and beverages
분리 기술
reversed phase
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일반 설명
Discovery® HS C18 HPLC column is specifically developed for pharmaceutical analyses and purification.
애플리케이션
- Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).
- A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).
- Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).
특징 및 장점
- Stable, low bleed for LC-MS applications
- Scalable from analytical to preparatory
- Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility
- Higher hydrophobicity for better resolution of difficult analytes
법적 정보
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Abad Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2782-2788 (2010-09-11)
A rapid, inexpensive, sensitive and specific HPLC-ECD method for the determination of lipoic acid in human plasma was developed and validated over the linearity range of 0.001-10μg/ml using naproxen sodium as an internal standard (IS). Extraction of lipoic acid and
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis
Fazli Khuda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 944, 114-122 (2013-12-10)
A simple, specific, precise and rapid RP-HPLC-UV method was developed for simultaneous determination of lumefantrine and its metabolite desbutyl lumefantrine in human plasma. Experimental parameters were optimized and the method was validated according to standard guidelines. The method showed adequate
Steinar Uran et al.
Journal of pharmaceutical and biomedical analysis, 44(4), 947-954 (2007-05-08)
Injection of hyperpolarized (13)C-labelled pyruvate ((13)C pyruvate) is under evaluation as an agent for medical metabolic imaging by measuring formation of (13)C lactate using magnetic resonance spectroscopy of the (13)C nuclei. A quantitative method for analysis of these (13)C-labelled substances
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
관련 콘텐츠
HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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