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Merck
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12023AST

Supelco

Astec® CHIROBIOTIC® T Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

동의어(들):

Chiral Stationary Phase Column T

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1 EA
₩3,312,554

₩3,312,554


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1 EA
₩3,312,554

About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

₩3,312,554


구입 가능 여부는 고객센터에 문의하십시오.

제품명

Astec® CHIROBIOTIC® T Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L63

설명

HPLC column

제품 라인

Astec®

포장

pkg of 1 ea

제조업체/상표

Astec®

파라미터

0-45 °C temperature
241 bar pressure (3500 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

15 cm × 4.6 mm

Matrix

High-purity silica gel particle platform
fully porous particle

기질 활성군

teicoplanin glycopeptide phase

입자 크기

5 μm

공극 크기

100 Å

작동 pH 범위

3.8-6.8

분리 기술

chiral

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

  • Bonded phase: Teicoplanin
  • Operating pH range: 3.8 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature

애플리케이션



  • Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples.: This study details the application of chiral liquid chromatography coupled with mass spectrometry for detecting salbutamol in urine, highlighting the column′s utility in sensitive biomedical assays ( Chan et al., 2016).


  • High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This research demonstrates the column′s effectiveness in enantioseparating specific cyclical amino acids, proving its versatility and importance in chiral separations ( Berkecz et al., 2009).


추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

D Abd el-Hady et al.
Journal of pharmaceutical and biomedical analysis, 37(5), 919-925 (2005-05-03)
A simple, sensitive and selective high performance liquid chromatographic method with UV detection for the chiral separation of racemic methotrexate (rac-Mtx) and enantiomeric purity of L-methotrexate in pharmaceutical formulations was developed and validated. The chiral separation was optimized studying both
M Sanghvi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 933, 37-43 (2013-07-23)
Due to the lack of sensitivity in current methods for the determination of fenoterol (Fen), a rapid LC-MS/MS method was developed for the determination of (R,R')-Fen and (R,R';S,S')-Fen in plasma and urine. The method was fully validated and was linear
Knut Gedicke et al.
Journal of chromatography. A, 1162(1), 62-73 (2007-03-03)
The separation of compounds possessing low solubility in the mobile phase could be improved by applying stronger solvents for dissolving the feed. A model system has been investigated with ethanol-water as the mobile phase, Chirobiotic T as the stationary phase
Yuan-Qing Xia et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 788(2), 317-329 (2003-04-23)
An automated online sample extraction method for rat plasma was developed and validated for the quantification of (R)- and (S)-propranolol following the intravenous administration of either the racemate or the individual enantiomers at 5 mg/kg. A dual-column extraction system coupled
Syntheses of racemic and non-racemic silicon- and germanium-containing a-amino acids of the formula type H2NCH(CH2ElR3)COOH (El=Si, Ge; R=organyl) and incorporation of d-H2NCH(CH2SiMe3)COOH and d-H2NCH(CH2GeMe3)COOH into biologically active decapeptides: a study on C/Si/Ge bioisosterism
Merget, Markus, et al.
Journal of Organometallic Chemistry, 628 (2), 183-194 (2001)

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