추천 제품
주관자
Novartis
SMILES string
CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl
InChI
1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
InChI key
YGWFCQYETHJKNX-UHFFFAOYSA-N
유전자 정보
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)
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관련 카테고리
생화학적/생리학적 작용
α-adrenoceptor agonist; imidazoline binding site ligand.
특징 및 장점
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Görkem Eskiizmir et al.
European journal of clinical pharmacology, 67(1), 19-23 (2010-11-12)
Oxymetazoline and xylometazoline are locally effective and direct acting drugs that relieve nasal congestion. The aim of this study was to objectively determine and compare the decongestive effects of oxymetazoline and xylometazoline in healthy subjects. The study population comprised thirty
I T Bognar et al.
The Journal of pharmacology and experimental therapeutics, 254(2), 702-710 (1990-08-01)
Rat hearts were isolated with the vagus nerves intact and perfused, and the neuronal acetylcholine stores were pulse labeled with [14C]choline. The overflow of [14C]choline/acetylcholine evoked by extrinsic vagus nerve stimulation (3 Hz and 720 pulses or 10 Hz and
Britta Haenisch et al.
Fundamental & clinical pharmacology, 24(6), 729-739 (2009-12-25)
Oxymetazoline and xylometazoline are both used as nasal mucosa decongesting α-adrenoceptor agonists during a common cold. However, it is largely unknown which of the six α-adrenoceptor subtypes are actually present in human nasal mucosa, which are activated by the two
Helle L Thulesius et al.
Rhinology, 49(1), 46-52 (2011-04-07)
Rhinomanometry before and after decongestion distinguishes a nasal airway organic stenosis from congestion of nasal mucosa in patients with nasal stuffiness. Together with rhinoscopy and patient history, it is used to decide if nasal surgery would benefit the patient. Rhinomanometry
Justin Cheung et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 24(5), 317-321 (2010-05-21)
The optimal topical anesthesia regimen for unsedated transnasal endoscopy is unknown. The addition of a nasal decongestant, such as xylometazoline (X), to a topical anesthestic may improve patient comfort. To determine the effectiveness of lidocaine (L) versus L plus X
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