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Merck
모든 사진(3)

주요 문서

V9378

Sigma-Aldrich

Vitamin K2

동의어(들):

Menaquinone 4, Menatetrenone

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250 MG
₩212,744
1 G
₩766,427

₩212,744


재고 있음세부사항


벌크 견적 요청

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250 MG
₩212,744
1 G
₩766,427

About This Item

실험식(Hill 표기법):
C31H40O2
CAS Number:
Molecular Weight:
444.65
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.79

₩212,744


재고 있음세부사항


벌크 견적 요청

양식

powder

Quality Level

색상

yellow

저장 온도

−20°C

SMILES string

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O

InChI

1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+

InChI key

DKHGMERMDICWDU-GHDNBGIDSA-N

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애플리케이션

  • Vitamin K2 ameliorates osteoarthritis by suppressing ferroptosis and extracellular matrix degradation through activation GPX4′s dual functions.: Vitamin K₂ is shown to have protective effects in osteoarthritis by inhibiting ferroptosis and preventing the degradation of the extracellular matrix. The study emphasizes the therapeutic potential of vitamin K₂ in managing joint health and reducing the progression of osteoarthritis (He et al., 2024).

생화학적/생리학적 작용

Menatetrenone (MK-4) is one of nine forms of vitamin K2 which is ubiquitously present in extrahepatic tissues. MK-4 has a number of metabolic and anti-neoplastic activities.

관련 제품

제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Carla A F Portela et al.
Journal of bacteriology, 196(11), 2012-2022 (2014-03-25)
Oxygen and oxidative stress have become relevant components in clarifying the mechanism that weakens bacterial cells in parallel to the mode of action of bactericidal antibiotics. Given the importance of oxidative stress in the overall defense mechanism of bacteria and
Jonna Weisell et al.
Scientific reports, 11(1), 3014-3014 (2021-02-06)
In calcific aortic valve disease (CAVD) progressive valvular calcification causes aortic valve dysfunction. CAVD has several risk factors such as age and dyslipidemia. Vitamin K was shown to inhibit vascular calcification in mice and valvular calcification in patients with CAVD.
Katheryne Z Edson et al.
Biochemistry, 52(46), 8276-8285 (2013-10-22)
Vitamin K plays an essential role in many biological processes including blood clotting, maintenance of bone health, and inhibition of arterial calcification. A menaquinone form of vitamin K, MK4, is increasingly recognized for its key roles in mitochondrial electron transport
Renata Tonhosolo et al.
FEBS letters, 584(23), 4761-4768 (2010-11-03)
Herein, we show that intraerythrocytic stages of Plasmodium falciparum have an active pathway for biosynthesis of menaquinone. Kinetic assays confirmed that plasmodial menaquinone acts at least in the electron transport. Similarly to Escherichia coli, we observed increased levels of menaquinone
Toshiro Sato et al.
Nutrition journal, 11, 93-93 (2012-11-13)
Vitamin K₂ contributes to bone and cardiovascular health. Therefore, two vitamin K₂ homologues, menaquinone-4 (MK-4) and menaquinone-7 (MK-7), have been used as nutrients by the food industry and as nutritional supplements to support bone and cardiovascular health. However, little is

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