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Merck
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주요 문서

V2501

Sigma-Aldrich

Snake venom from Vipera russelli (Russell′s Viper)

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100 MG
₩532,875

₩532,875


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100 MG
₩532,875

About This Item

UNSPSC 코드:
12352202

₩532,875


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

저장 온도

−20°C

Quality Level

애플리케이션

Snake venom from Vipera russelli (Russell′s Viper) has also been used as a positive control in indirect and sandwich enzyme-linked immunosorbent assay (ELISA) to study the performance of the immunochromatographic test (ICT)-Viper in venom detection in vitro and the detection of clinical envenoming, respectively.[1]
Snake venom from Vipera russelli (Russell′s Viper) has been used for extraction of coagulant protein for complex generation with bovine X factor.[2]

생화학적/생리학적 작용

Snake venom can impose death on humans and animals.[3] Nevertheless, snake venom also exhibits anti-bacterial and wound healing properties.[4] Therefore, it is used as a therapeutic for treating various diseases including thrombosis, arthritis, and cancer.[3]
Snake venom from Russell′s Viper is rich in toxins and proteinase inhibitors.[5] The receptor from Vipera russelli β-RTX, interacts with monoamines and opiate and prevents their interaction with native receptors.[6] The proteases from Russell′s Viper mediate coagulation in human plasma.[7] The neurotoxicity of the venom is contributed by phospholipases.[8]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Sanjoy Kumar Pal et al.
Indian journal of experimental biology, 40(12), 1353-1358 (2003-09-17)
Snake bite injuries and death are socio-medical problems of considerable magnitude. In India a large number of people suffer and die every year due to snake venom poisoning. Snake venom, though greatly feared, is a natural biological resource, containing several
Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains.
Takeya H, et al.
The Journal of Biological Chemistry, 267(20), 14109-14117 (1992)
beta-RTX. A receptor-active protein from Russell's viper (Vipera russelli russelli) venom.
Bevan P and Hiestand P
The Journal of Biological Chemistry, 258(8), 5319-5326 (1983)
Characterization and molecular cloning of neurotoxic phospholipases A2 from Taiwan viper (Vipera russelli formosensis)
WANG YM, et al.
European Journal of Biochemistry, 209(2), 635-641 (1992)
Snake Venom Proteinase Inhibitors: II. Chemical Structure of Inhibitor II Isolated from the Venom of Russell's viper (Vipera russelli)
TAKAHASHI H, et al.
Journal of Biochemistry, 76(4), 721-733 (1974)

질문

1–2 / 2 질문  
  1. How can V2501 be diluted? Where can I find the documentation for this process?

    1 답변
    1. The supplier has provided the following information: store the powder at -20°C and dissolve it in sterile water, typically at 20 mg/ml. The solution may appear slightly hazy. It is recommended to store the solution in aliquots at -80°C, but -20°C is suitable for a short period of time, although the supplier does not define what is meant by a 'short period'. It is advised to avoid repeated freezing and thawing cycles, and the supplier suggests aliquoting the product once in solution.

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  2. Origin of venom RVV, do you issue Cites certificate?

    1 답변
    1. See the link below to review a sample Certificate of Origin for this product:
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COO/Q12/V2501-100MGSLCL9857.pdf

      These documents are lot-specific and may be supplied by our Technical Service team. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Documentation" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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