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Merck
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주요 문서

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UC282

Sigma-Aldrich

6β-Hydroxytestosterone

≥97% (HPLC)

동의어(들):

4-Androstene-6β,17β-diol-3-one, 6β, 17β,-Dihydroxyandrost-4-en-3-one

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About This Item

실험식(Hill 표기법):
C19H28O3
CAS Number:
62-99-7
Molecular Weight:
304.42
MDL number:
MFCD00171612
UNSPSC 코드:
12161501
PubChem Substance ID:
24900687

분석

≥97% (HPLC)

약물 제어

regulated under CDSA - not available from Sigma-Aldrich Canada

색상

white to off-white

mp

≥205 °C

solubility

acetonitrile: soluble
ethanol: soluble
methanol: soluble

저장 온도

2-8°C

SMILES string

C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1

InChI key

XSEGWEUVSZRCBC-ZVBLRVHNSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

6β-Hydroxytestosterone has been used for CYP3A activity assays in rat hepatocytes and has also been used for CYP3A4 substrate selection studies.

생화학적/생리학적 작용

6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic.

제조 메모

6β-Hydroxytestosterone is soluble in methanol, acetonitrile and ethanol.

교체됨

제품 번호
설명
가격

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H351,H360

예방조치 성명서

P201 - P281 - P308 + P313

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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시험 성적서(COA)

Lot/Batch Number
068K3351
037K3851

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yoshitaka Miyamoto et al.
Cell transplantation, 18(5), 677-681 (2009-09-25)
Three-dimensional culture procedures have attracted attention in various fields of cell biology. A newly developed cell array assisted in the formation of hepatocyte spheroids by two innovations: 1) micropatterning by a hydrophilic polymer, and 2) the use of bovine carotid
Aleksandra Galetin et al.
The Journal of pharmacology and experimental therapeutics, 314(1), 180-190 (2005-03-24)
The complexity of in vitro kinetic phenomena observed for CYP3A4 substrates (homo- or heterotropic cooperativity) confounds the prediction of drug-drug interactions, and an evaluation of alternative and/or pragmatic approaches and substrates is needed. The current study focused on the utility
Jin Wu et al.
Analytical chemistry, 79(12), 4657-4665 (2007-05-15)
This paper describes the development of a high-throughput method for the analysis of cytochrome P450 (CYP) inhibition assay incubation samples using laser diode thermal desorption interfaced with atmospheric pressure chemical ionization mass spectrometry (LDTD-APCI-MS). Data for the CYP isoforms 3A4
Takeshi Akiyoshi et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(4), 724-728 (2011-01-08)
CYP3A4, an important drug-metabolizing enzyme, is known to have genetic variants. We have previously reported that CYP3A4 variants such as CYP3A4.2, 7, 16, and 18 show different enzymatic kinetics from CYP3A4.1 (wild type). In this study, we quantitatively investigated the
Furong Qiu et al.
Xenobiotica; the fate of foreign compounds in biological systems, 40(12), 800-806 (2010-10-23)
This study evaluated the in vitro activation of CYP3A-mediated midazolam 1-hydroxylation and testosterone 6β-hydroxylation by tanshinone I, tanshinone IIA, and cryptotanshinone. The abilities of tanshinones to activate CYP3A-mediated midazolam 1-hydroxylation and testosterone 6β-hydroxylation in human liver microsomes (HLMs) were tested.
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