T9531

D-(+)-Trehalose dihydrate

≥99% (HPLC), from Saccharomyces cerevisiae

• 동의어(들): Trehalose dihydrate, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• 실험식(Hill 표기법): C₁₂H₂₂O₁₁ · 2H₂O
• CAS Number: 6138-23-4
• Molecular Weight: 378.33
• Beilstein: 5322018
• EC Number: 202-739-6
• MDL number: MFCD00071594
• UNSPSC 코드: 12352201
• PubChem Substance ID: 57654693
• NACRES: NA.25

속성

• 생물학적 소스: Saccharomyces cerevisiae
• 분석: ≥99% (HPLC)
• 양식: powder
• 광학 활성: [α]20/D 174 to 182 °, c = 7% (w/v) in water
• 기술: HPLC: suitable; PCR: suitable; cell based assay: suitable; cryopreservation: suitable
• 불순물: ≤5.0% EtOH; <20 ppm Trace metals
• 색상: white
• mp: 97-99 °C
• solubility: water: 50 mg/mL, clear, colorless
• 응용 분야: advanced drug delivery; agriculture; cell analysis; life science and biopharma; sample preparation
• 저장 온도: room temp
• SMILES string: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• InChI key: DPVHGFAJLZWDOC-PVXXTIHASA-N

설명

일반 설명

Trehalose, also known as mycose or tremalose, is a nonreducing disaccharide of glucose commonly found in fungi, bacteria, and invertebrates. Its presence in these organisms highlights its significance in various biological processes and potential applications in biochemical research and cell culture studies.

애플리케이션

D-(+)-Trehalose dihydrate has been used:

• as a transcription factor EB (TFEB) to study its effects on an autophagy-lysosomal system in human silicosis alveolar macrophages[1]
• as stabilizing excipient in spray-dried protein formulations[2]
• as a cryoprotectant to study its effects on mouse testicular cell suspensions[3]

생화학적/생리학적 작용

D-(+)-Trehalose shows anti-desiccant and cryopreservative activities.[4] It acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon.[5] Trehalose is involved in the food, cosmetic, and pharmaceutical industries.[6] It plays a vital role in the survival of certain insects and plants known as anhydrobionts during harsh environments such as high rates of dehydration.[7]

품질

Reduced metal ion content.

제조 메모

Prepared by ion exchange chromatography.

기타 정보

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)