T2896
Triflupromazine hydrochloride
동의어(들):
N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine monohydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H19F3N2S · HCl
CAS Number:
Molecular Weight:
388.88
Beilstein:
3801519
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
추천 제품
SMILES string
Cl.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F
InChI
1S/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key
FTNWXGFYRHWUKG-UHFFFAOYSA-N
유전자 정보
human ... DRD2(1813)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Triflupromazine hydrochloride has been used for the screening of inhibitors of S. mansoni miracidial transformation5. It has also been used to study its intracellular localization in central nervous system cells using secondary ion mass spectrometry microscopy6.
생화학적/생리학적 작용
Triflupromazine is a D2 dopamine antagonist and a phenothiazine antipsychotic. It is also a potent tranquilizer7 and can significantly reduce body temperature8.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The structure of triflupromazine, a phenothiazine 'tranquilizer' drug molecule.
Phelps, D. W., and Cordes, A. W.
Acta Crystallographica Section B, Structural Crystallography and Crystal Chemistry, 30(12), 2812-2816 (1974)
M Tatsumi et al.
European journal of pharmacology, 368(2-3), 277-283 (1999-04-08)
Using radioligand binding techniques, we determined the equilibrium dissociation constants (K(D)) for 37 neuroleptics and one metabolite of a neuroleptic (haloperidol metabolite) for the human serotonin, norepinephrine, and dopamine transporters with [3H]imipramine, [3H]nisoxetine, and [3H]WIN35428, respectively. Among neuroleptics, the four
A study of triflupromazine in dominant-lethal, cytogenetic and host-mediated assays.
V A Ray et al.
Mutation research, 18(3), 301-309 (1973-06-01)
D Jovanović-Mićić et al.
European journal of pharmacology, 272(1), 21-30 (1995-01-05)
Intracerebroventricular injection of dopamine (0.5-4.0 mg) produced dose-dependent and short-lasting emesis (1-8 min) in cats, which was abolished after ablation of the area postrema. Relatively selective alpha 2-adrenoceptor antagonists (yohimbine and idazoxan) and a mixed alpha 1- and alpha 2-adrenoceptor
L L Zhang et al.
Biology of the cell, 74(1), 99-103 (1992-01-01)
The intracellular localization of two neurotropic drugs, flunitrazepam (benzodiazepine) and triflupromazine (phenothiazine), was studied by secondary ion mass spectrometry microscopy (SIMS) in three varieties of cells. The images of the intracellular distributions of the two drugs are easily obtained by
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