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T2807

Thymidine Phosphorylase, recombinant from Escherichia coli

recombinant, expressed in E. coli, buffered aqueous solution, ≥500 units/mL

동의어(들):

Thymidine:orthophosphate deoxy-D-ribosyltransferase

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크기 선택

보기 변경
사이즈/SKU재고 정보가격 (VAT 별도)
500 units
구입 가능 여부는 고객센터에 문의하십시오.
₩283,490
1000 units
구입 가능 여부는 고객센터에 문의하십시오.
₩371,186
5000 units
구입 가능 여부는 고객센터에 문의하십시오.
₩1,266,923

제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
EC 번호:
Recombinant:
expressed in E. coli
Concentration:
≥500 units/mL

₩283,490


구입 가능 여부는 고객센터에 문의하십시오.

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recombinant

expressed in E. coli

Quality Segment

form

buffered aqueous solution

concentration

≥500 units/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

Escherichia coli K12 ... deoA(948901)

General description

Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation.

Application

Thymidine phosphorylase has been used in a study to assess TAS-102 treatment in patients with advanced solid tumors. Thymidine phosphorylase has also been used in a study to investigate antitumor effects of the FP3 protein on patient-derived tumor tissue xenograft models of primary colon carcinoma.

Biochem/physiol Actions

An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway.
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.

Physical form

Solution in 0.5 M potassium phosphate containing 2 mM uracil, 0.02% sodium azide and bovine serum albumin

Preparation Note

Cloned from E. coli and produced in overexpressing E. coli

Other Notes

One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25°C.

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 1

이 품목
T6632SRE0006F3174
description

recombinant, expressed in E. coli, buffered aqueous solution, ≥500 units/mL

description

recombinant, expressed in E. coli, buffered aqueous solution, ≥900 units/mL, 0.2 μm filtered

description

recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500 units/mL

description

≥90% (SDS-PAGE), buffered aqueous glycerol solution, >20,000 units/mg protein, suitable for genomic analysis

Gene Information

Escherichia coli K12 ... deoA(948901)

Gene Information

Escherichia coli K12 ... deoA(948901)

Gene Information

Escherichia coli ... deoA(948901)

Gene Information

Escherichia coli CFT073 ... mutM(1038243)
Escherichia coli K12 ... mutM(946765)

concentration

≥500 units/mL

concentration

≥900 units/mL

concentration

≥500 units/mL

concentration

-

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

UniProt accession no.

P07650

UniProt accession no.

P07650

UniProt accession no.

P07650

UniProt accession no.

P05523

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C


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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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