SRP8028

DR6 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• 동의어(들): CD358, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in HEK 293 cells
• 분석: >95% (SDS-PAGE)
• 양식: lyophilized
• 분자량: ~80 kDa by SDS-PAGE
• 포장: pkg of 50 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: <0.1 EU/μg endotoxin, tested
• 색상: white
• UniProt 수납 번호: O75509
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... TNFRSF21(27242)

설명

일반 설명

DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

물리적 형태

Lyophilized from PBS.

재구성

Reconstitute with 50 μL deionized water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.

기타 정보

The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable