SRP6278

TDRD12-BD2 (908-999) his tag human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 동의어(들): ECAT8
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥98% (SDS-PAGE)
• 양식: liquid
• 분자량: 13 kDa
• 포장: pkg of 1 mg; pkg of 100 μg; pkg of 20 μg
• 농도: 2 mg/mL
• UniProt 수납 번호: Q587J7
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... TDRD12(91646)

설명

일반 설명

Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.

물리적 형태

rh-TDRD12-BD2 is supplied as a solution in PBS Buffer containing 10% glycerol.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable