SRP6251

CCL6 from mouse

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

• 동의어(들): C10, CCL6, MRP-1, SCYA6
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• 재조합: expressed in HEK 293 cells
• 태그: 6-His tagged (C-terminus)
• 분석: ≥95% (SDS-PAGE)
• 양식: lyophilized powder
• 분자량: calculated mol wt 11.4 kDa (The predicted N-terminus is Gly22.); observed mol wt 14 kDa by SDS-PAGE (reducing)
• 포장: pkg of 10 μg
• 불순물: <1 EU/μg endotoxin (LAL test)
• UniProt 수납 번호: P27784
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... CCL6(20305)

설명

일반 설명

Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family,[1] was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM-CSF. CCL6 has only been identified in rodents. A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages,[1] where it is strongly induced upon GM-CSF stimulation. Mouse CCL6 expression was also shown to be strongly induced by interleukin-4 (IL-4) in mouse macrophages and by cytokine IL-13 in mouse lung.[2] Mouse CCL6 is located on chromosome 11.[3] The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.[2]

물리적 형태

Lyophilized from 0.22 μm filtered solution in PBS. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

재구성

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable