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Merck
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주요 문서

SRP6182

Sigma-Aldrich

Human Serum Albumin

≥98% (SDS-PAGE)

동의어(들):

GIG20, GIG42, HSA, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, serum albumin

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모든 사진(1)

About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

human

분석

≥98% (SDS-PAGE)

양식

liquid

분자량

66.4 kDa

포장

pkg of 1 mg

농도

10 mg/mL

UniProt 수납 번호

P02768

배송 상태

wet ice

저장 온도

2-8°C

유전자 정보

human ... ALBU(213)

일반 설명

The gene HSA (human serum albumin) is mapped to human chromosome 4q13.3.[1] The gene encodes a protein of 585 amino acids with a molecular weight of 66.4kDa.[2] HSA is the most abundant protein in the plasma and has many metal-binding sites.[3][4]

애플리케이션

HSA (human serum albumin) has been used for the development of automated dye-binding method for serum albumin determination using bromcresol purple.[5] It has also been used to study effect of HSA on DNA transfection by lipoplexes.[6]

생화학적/생리학적 작용

HSA (human serum albumin) mainly works as a carrier for various nutrients, metabolites and xenobiotics. It interacts with plasma zinc and regulates uptake of zinc in cells.[4] HSA plays a crucial role in drug pharmacokinetics.[3] It also controls oncotic pressure and volume of the blood.[7] Mutations in the gene are linked with congenital analbuminemia and familial dysalbuminemic hyperthyroxinemia.[1][8]

물리적 형태

Sterile filtered yellowish liquid.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
8K25L40160
8K24L40160
8F03L40160
8E09L40160
7H17L40160

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum.
Sim?es S
Biochimica et Biophysica Acta, 1463, 459-469 (2000)
Structure and ligand binding properties of human serum albumin.
Kragh-Hansen U
Danish Medical Bulletin, 37, 57-84 (1990)
New automated dye-binding method for serum albumin determination with bromcresol purple.
Pinnell AE and Northam BE
Clinical Chemistry, 24, 80-86 (1978)
A nucleotide deletion and frame-shift cause analbuminemia in a Turkish family.
Caridi G
Biochemia Medica, 26, 264-271 (2016)
A nucleotide insertion and frameshift cause analbuminemia in an Italian family.
Watkins S
Proceedings of the National Academy of Sciences of the USA, 91, 2275-2279 (1994)
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질문

1–3 / 3 질문  

  1. What solvent can I use to dissolve albumin?

    1 답변

    1. This product is a prepared solution at 10 mg/mL. The 1 mg package will have a volume of 100 ul. The formulation of the diluent used to prepare this product is proprietary, however this product can be further diluted in PBS., medium, or other aqueous buffers. HSA, in powder form, can be dissolved in water or other buffers at up to 50 mg/mL.

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  2. Hi, this products CoA and SDS don't include the concentration. Is there a way we can get updated documentation to include the 10mg/mL?

    1 답변

    1. The final concentration of this product (SRP6182) is not tested or reported. This is a part of the production process. Should this information be required for your application see products A9080 or A6784. These are 30% and 10% solutions, respectively. The lot specific certificate of analysis for these products confirms the final concentration. The product can be further diluted based on this information to the desired concentration.

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  3. It says this is 1 mg and 200 mg/mL. That would mean the product is 5 microliters. Is this correct?

    1 답변

    1. This product is supplied at a concentration of 10mg/mL; therefore 1mg of material is contained in a volume of 100uL.

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