SRP6036

CD-14 from mouse

recombinant, expressed in CHO cells, 90-95% (SDS-PAGE)

• 동의어(들): CD14, Cluster of differentiation 14
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• 재조합: expressed in CHO cells
• 분석: 90-95% (SDS-PAGE)
• 양식: lyophilized
• 분자량: 50.0 kDa
• 포장: pkg of 10 μg
• 불순물: Endotoxin, tested
• NCBI 수납 번호: P10810
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... CD14(12475)

설명

일반 설명

CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macrophages and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein. This is a His-tagged protein.

물리적 형태

Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2

재구성

Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable