SRP5269

HDAC7, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 동의어(들): DKFZp586J0917, FLJ99588, HD7A, HDAC7A
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 재조합: expressed in baculovirus infected Sf9 cells
• 분석: ≥70% (SDS-PAGE)
• 양식: buffered aqueous glycerol solution
• 특이 활성도: 64-96 RLU/min·ng
• 분자량: ~80 kDa
• NCBI 수납 번호: NM_015401
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... HDAC7(51564)

설명

일반 설명

HDAC7 or Histone deacetylase 7 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by HDAC7 gene has sequence homology to members of the histone deacetylase family whose protein promotes repression mediated via the transcriptional co-repressor SMRT. HDAC7 interacts with β-catenin keeping endothelial cells in a low proliferation stage. HDAC7 regulates NUR77 and apoptosis in developing thymocytes. HDAC7 is expressed in human osteoarthritis that contributes to cartilage degradation via promoting MMP-13 gene expression.

물리적 형태

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

제조 메모

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable