SRP4503

FABP3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 동의어(들): Fatty acid-binding protein heart, H-FABP, Heart-type fatty acid-binding protein, M-FABP, Mammary-derived growth inhibitor, Muscle fatty acid-binding protein
• MDL number: MFCD00285932
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥98% (SDS-PAGE)
• 양식: lyophilized
• 분자량: ~19 kDa
• 포장: pkg of 100 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: endotoxin, tested
• NCBI 수납 번호: P05413
• UniProt 수납 번호: P05413
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... FABP3(2170)

설명

일반 설명

Fatty acid binding proteins (FABPs) are intracellular proteins with a low molecular weight. They exhibit high affinity for small lipophilic ligands. FABP-3 is expressed in the skeletal muscle, heart, brain and brown adipose tissue. The gene encoding it is localized on human chromosome 1p35.[1][2]

생화학적/생리학적 작용

Studies suggest that fatty acid binding protein (FABPs) are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation. FABPs have been associated with diabetes, obesity, atherosclerosis and brain function. FABP-3 has a role in glucose and lipid metabolism. It also modulates polysaturated fatty acid uptake and metabolism in neurons. The protein has been associated with schizophrenia, Down′s syndrome, Alzheimer′s disease and autism spectrum disorder.[1]

물리적 형태

Sterile filtered and Lyophilized without additives.

재구성

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable