콘텐츠로 건너뛰기
Merck
모든 사진(1)

문서

SRP4304

Sigma-Aldrich

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

동의어(들):

Nerve Growth Factor β, Ngf, Ngfb

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

mouse

재조합

expressed in E. coli

분석

≥98% (SDS-PAGE)

형태

lyophilized

효능

0.2 ng/mL ED50

분자량

~13.4 kDa

포장

pkg of 20 μg

불순물

endotoxin, tested

NCBI 수납 번호

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

mouse ... Ngf(18049)

일반 설명

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family. The active form of human NGF-β is a homodimer, non-glycosylated chain.

생화학적/생리학적 작용

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. It brings pro-survival effects with the help of receptor tyrosine kinase TrkA. NGF-β is associated with diabetic neuropathy and ischemic heart disease. It is also involved in airway nerve system. NGF-β is also responsible for the pain which is linked with osteoarthritis (OA). It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.

물리적 형태

Lyophilized without any additives.

재구성

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Nerve growth factor rescues diabetic mice heart after ischemia/reperfusion injury via up-regulation of the TRPV1 receptor.
Zheng LR
The Journal of Diabetic Complications, 29, 323-328 (2015)
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner.
Mnich K
Cell Death & Disease, 5, e1202-e1202 (2014)
Up-regulation of nerve growth factor in cholestatic livers and its hepatoprotective role against oxidative stress.
Tsai MS
PLoS ONE, 9, e112113-e112113 (2014)
Alex Straiker et al.
Molecules (Basel, Switzerland), 26(17) (2021-09-11)
Cannabis contains more than 100 phytocannabinoids. Most of these remain poorly characterized, particularly in neurons. We tested a panel of five phytocannabinoids-cannabichromene (CBC), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabidivarinic acid (CBDVA), and Δ9-tetrahydrocannabivarin (THCV) in two neuronal models, autaptic hippocampal
Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain.
Arthritis Research & Therapy, 16, R16-R16 (2014)

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.