추천 제품
생물학적 소스
mouse
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
형태
lyophilized
효능
0.2 ng/mL ED50
분자량
~13.4 kDa
포장
pkg of 20 μg
불순물
endotoxin, tested
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
mouse ... Ngf(18049)
일반 설명
Nerve growth factor-β (NGF-β) belongs to the neurotrophin family. The active form of human NGF-β is a homodimer, non-glycosylated chain.
생화학적/생리학적 작용
Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. It brings pro-survival effects with the help of receptor tyrosine kinase TrkA. NGF-β is associated with diabetic neuropathy and ischemic heart disease. It is also involved in airway nerve system. NGF-β is also responsible for the pain which is linked with osteoarthritis (OA). It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.
물리적 형태
Lyophilized without any additives.
재구성
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Nerve growth factor rescues diabetic mice heart after ischemia/reperfusion injury via up-regulation of the TRPV1 receptor.
The Journal of Diabetic Complications, 29, 323-328 (2015)
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner.
Cell Death & Disease, 5, e1202-e1202 (2014)
Up-regulation of nerve growth factor in cholestatic livers and its hepatoprotective role against oxidative stress.
PLoS ONE, 9, e112113-e112113 (2014)
Molecules (Basel, Switzerland), 26(17) (2021-09-11)
Cannabis contains more than 100 phytocannabinoids. Most of these remain poorly characterized, particularly in neurons. We tested a panel of five phytocannabinoids-cannabichromene (CBC), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabidivarinic acid (CBDVA), and Δ9-tetrahydrocannabivarin (THCV) in two neuronal models, autaptic hippocampal
Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain.
Arthritis Research & Therapy, 16, R16-R16 (2014)
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