일반 설명
Human cKit (D816V) ( GenBank Accession No. NM_000222), amino acids 544-end with N-terminal His-tag, MW=50 kDa, expressed in an Baculovirus infected Sf9 cell expression system.
애플리케이션
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
물리적 형태
Fomulated in 25 mM Tris-HCl, pH 8.0, 138 mM NaCl, 0.05% Tween-20, 3 mM DTT and 10% glycerol.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
Mauro Picardo et al.
The Journal of investigative dermatology, 131(6), 1182-1185 (2011-05-14)
Cutaneous pigmentation is regulated by a complex melanogenic network in which skin cells synthesize growth factors and cytokines. Mutations in genes encoding these regulators modify their expression and/or functionality, leading to altered signaling pathways and contributing to altered skin phenotypes.
Y Yarden et al.
The EMBO journal, 6(11), 3341-3351 (1987-11-01)
Structural features of v-kit, the oncogene of HZ4 feline sarcoma virus, suggested that this gene arose by transduction and truncation of cellular sequences. Complementary DNA cloning of the human proto-oncogene coding for a receptor tyrosine kinase confirmed this possibility: c-kit
활성 필터
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