SML3947
PSB12379
≥98% (HPLC)
동의어(들):
Placeholder name, N-(Phenylmethyl)-adenosine-5′-[hydrogen P-(phosphonomethyl)phosphonate] sodium salt, N6-Benzylpurine riboside-5′-O-[(phosphonomethyl)-phosphonic acid sodium salt
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모든 사진(2)
크기 선택
보기 변경
5 MG
₩274,253
25 MG
₩1,101,478
About This Item
실험식(Hill 표기법):
C18H23N5O9P2. xNa
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to beige
solubility
H2O: 2 mg/mL, clear
저장 온도
2-8°C
생화학적/생리학적 작용
Potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor.
PSB12379 is a potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor (recombinant human/rat eN Ki = 2.21/9.03 nM; human serum eN Ki = 18.8 nM; Ki >>10 μM against NTPDase 1/2/3 & NPP 1/2/3). Umbilical cord mesenchymal stem cell-derived small extracellular vesicles (UCMSC-sEV) is reported to promote the proliferation and migration of pediatric urethral smooth muscle cells (PUSMCs) in cultures by CD73-catalyzed production of adenosine, which can be blocked by PSB12379.
PSB12379 is a potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor (recombinant human/rat eN Ki = 2.21/9.03 nM; human serum eN Ki = 18.8 nM; Ki >>10 μM against NTPDase 1/2/3 & NPP 1/2/3). Umbilical cord mesenchymal stem cell-derived small extracellular vesicles (UCMSC-sEV) is reported to promote the proliferation and migration of pediatric urethral smooth muscle cells (PUSMCs) in cultures by CD73-catalyzed production of adenosine, which can be blocked by PSB12379.
주의사항
Hygroscopic
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
?,?-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors
Journal of medicinal chemistry, 58(15), 6248-6263 (2015)
A Body of Circumstantial Evidence for the Irreversible Ectonucleotidase Inhibitory Action of FSCPX, an Agent Known as a Selective Irreversible A1 Adenosine Receptor Antagonist So Far
International Journal of Molecular Sciences, 22(18), 9831-9831 (2021)
CD73-Positive Small Extracellular Vesicles Derived From Umbilical Cord Mesenchymal Stem Cells Promote the Proliferation and Migration of Pediatric Urethral Smooth Muscle Cells Through Adenosine Pathway
Frontiers in Bioengineering and Biotechnology, 10, 895998-895998 (2022)
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