SML3530

DMA-135

≥98% (HPLC)

• 동의어(들): 3-​amino-​N-​(aminoiminomethyl)​-​5-​(dimethylamino)​-​6-​(2-​phenylethynyl)​-2-​pyrazinecarboxamide hydrochloride
• 실험식(Hill 표기법): C₁₆H₁₇N₇O · xHCl
• CAS Number: 2237925-62-9
• Molecular Weight: 323.35 (free base basis)
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CN(C1=C(N=C(C(N)=N1)C(NC(N)=N)=O)C#CC2=CC=CC=C2)C.[xHCl]

설명

생화학적/생리학적 작용

DMA-135 is a cell penetrant and potent inhibitor of human enterovirus 71 (EV71) translation and replication that targets the IRES domain of EV71. DMA-135 binds allosterically to EV71 SLII RNA and stabilizes ternary complex consisting of AUF1-SLII-DMA-135. Also, previous data indicate that DMA-135 exhibit comparable affinity to HIV-1-TAR and HIV-2-TAR.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable