SML2912
UNC4976 Trifluoroacetate
≥95% (HPLC)
동의어(들):
Methyl N6-(bicyclo[2.2.1]heptan-2-yl)-N2-(4-(tert-butyl)benzoyl)-L-phenylalanyl-L-alanyl-L-leucyl-N6-methyl-L-lysyl-L-serinate trifluoroacetate
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C47H70N6O8 · xC2HF3O2
Molecular Weight:
847.09 (free base basis)
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.
추천 제품
Quality Level
분석
≥95% (HPLC)
양식
film
색상
white to beige
배송 상태
wet ice
저장 온도
−20°C
SMILES string
N([C@@H](CO)C(=O)OC)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)c4ccc(cc4)C(C)(C)C)Cc3ccccc3)C)CC(C)C)CCCCN(C1C2CC(C1)CC2)C
InChI key
UKWNWTBRKZUHGX-GKUWNYOMSA-N
생화학적/생리학적 작용
UNC4976 is a cell penetrant and potent positive allosteric modulator (PAM) of CBX7 chromodomain of polycomb repressive complex 1 that enhances CBX7 chromodomain affinity for nucleic acids. UNC4976 substantially potentiates the expression of polycomb target genes.
cell penetrant and potent positive allosteric modulator (PAM) of CBX7 chromodomain
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Kelsey N Lamb et al.
Cell chemical biology, 26(10), 1365-1379 (2019-08-20)
Polycomb-directed repression of gene expression is frequently misregulated in human diseases. A quantitative and target-specific cellular assay was utilized to discover the first potent positive allosteric modulator (PAM) peptidomimetic, UNC4976, of nucleic acid binding by CBX7, a chromodomain methyl-lysine reader
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
