NV-5440 is a cell penetrant, potent and selective class I glucose transporters (GLUT1) inhibitor that selectively inhibits mTORC1 pathway in vivo. NV-5440 acts as a potent inhibitor of glycolysis in cells.
cell penetrant, potent and selective GLUT1 inhibitor that selectively inhibits mTORC1 pathway in vivo
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Cell chemical biology, 26(9), 1203-1213 (2019-06-25)
The mechanistic target of rapamycin (mTOR) is a central regulator of cellular metabolic processes. Dysregulation of this kinase complex can result in a variety of human diseases. Rapamycin and its analogs target mTORC1 directly; however, chronic treatment in certain cell
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