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Merck
모든 사진(1)

문서

SML2764

Sigma-Aldrich

Pitofenone hydrochloride

≥98% (HPLC)

동의어(들):

2-[4-[2-(1-Piperidinyl)ethoxy]benzoyl]-benzoic acid methyl ester hydrochloride, Algifen Neo

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About This Item

실험식(Hill 표기법):
C22H25NO4 · HCl
CAS Number:
Molecular Weight:
403.90
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

형태

powder

저장 조건

desiccated

색상

white to beige

solubility

H2O: 2 mg/mL, clear

저장 온도

−20°C

InChI

1S/C22H25NO4.ClH/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23;/h3-4,7-12H,2,5-6,13-16H2,1H3;1H

InChI key

ZRFIFDFEDPJBII-UHFFFAOYSA-N

생화학적/생리학적 작용

Pitofenone is a potent muscarinic receptor antagonist. Pitofenone in combination with diclofenac exhibits potent antispasmodic effect in cholinergic spasm.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

K V Marthak et al.
Current medical research and opinion, 12(6), 366-373 (1991-01-01)
A single-blind, randomized clinical trial was carried out to compare the analgesic effectiveness in patients with renal colic of single intramuscular doses of diclofenac sodium (75 mg) versus a dipyrone (1 g)/spasmolytics combination, and diclofenac sodium (75 mg) versus pethidine
Shrinivas K Kulkarni et al.
Indian journal of experimental biology, 42(6), 567-569 (2004-07-21)
Biliary, ureteric and intestinal colic are extremely common clinical conditions associated with smooth muscle spasm. In the present study, antispasmodic activity was carried out against acetylcholine (10-640 ng/ml)-induced contractions on guinea pig ileum. Acetylcholine (10-640 ng/ml) induced concentration-dependent contraction of
J Sanahuja et al.
DICP : the annals of pharmacotherapy, 24(4), 361-364 (1990-04-01)
A comparative, randomized, double-blind study of diclofenac sodium 75 mg im versus Baralgin (a combination drug composed of dipyrone and two spasmolytics) 5 mL iv was performed on 57 patients with renal colic. Both groups were comparable as to age

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