SML2630
Intronistat B hydrobromide
≥98% (HPLC)
동의어(들):
N-(2-(Pyrrolidin-1-yl)ethyl)-2-(3,4,5-trihydroxybenzoyl) benzofuran-5-carboxamide hydrobromide
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩102,109
25 MG
₩412,192
모든 사진(1)
크기 선택
보기 변경
5 MG
₩102,109
25 MG
₩412,192
About This Item
실험식(Hill 표기법):
C22H22N2O6 · xHBr
Molecular Weight:
410.42 (free base basis)
UNSPSC 코드:
51111800
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to dark gray
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
생화학적/생리학적 작용
Inhibitor of the self-splicing group IIB intron found in fungi
Intronistat B is a potent inhibitor of the self-splicing group IIB intron, a mitochondrial RNA tertiary structure necessary for respiration in fungi, yeast and plants, but not found in vertebrates. Intronistat B was found to have antifungal activity comparable to that of amphotericin B in inhibiting growth of the Candida parapsilosis. It did not inhibit spliceosomal processing, group I intron splicing or splicing of group II introns from subclasses other than subclass IIB and was not toxic to human cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
Olga Fedorova et al.
Nature chemical biology, 14(12), 1073-1078 (2018-10-17)
Specific RNA structures control numerous metabolic processes that impact human health, and yet efforts to target RNA structures de novo have been limited. In eukaryotes, the self-splicing group II intron is a mitochondrial RNA tertiary structure that is absent in
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