SML2627
Connexin43 mimetic peptide 5 trifluoroacetate salt
≥95% (HPLC)
동의어(들):
Peptide 5 trifluoroacetate salt, VDCFLSRPTEKT trifluoroacetate salt, Val-Asp-Cys-Phe-Leu-Ser-Arg-Pro-Thr-Glu-Lys-Thr trifluoroacetate salt
로그인조직 및 계약 가격 보기
크기 선택
1 MG
₩268,062
모든 사진(1)
크기 선택
보기 변경
1 MG
₩268,062
About This Item
실험식(Hill 표기법):
C60H98N16O20S · xC2HF3O2
CAS Number:
Molecular Weight:
1395.58 (free base basis)
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
분석
≥95% (HPLC)
양식
lyophilized powder
색상
white to beige
저장 온도
−20°C
생화학적/생리학적 작용
Connexin43 mimetic peptide 5 is a blocker of connexin43 hemichannels that inhibits gap junction channels following CNS injury. Peptide 5 was designed to bind to extracellular regions of the connexin43 protein.
blocker of connexin43 hemichannels that inhibits gap junction channels following CNS injury
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Yilin Mao et al.
Experimental brain research, 235(10), 3033-3048 (2017-07-21)
Systemic administration of a Connexin43 mimetic peptide, Peptide5, has been shown to reduce secondary tissue damage and improve functional recovery after spinal cord injury (SCI). This study investigated safety measures and potential off-target effects of Peptide5 systemic administration. Rats were
Yeri Kim et al.
Biochimica et biophysica acta. General subjects, 1861(2), 68-78 (2016-11-07)
Non-selective Connexin43 hemichannels contribute to secondary lesion spread. The hemichannel blocking peptidomimetic Peptide5, derived from the second extracellular loop of the human Connexin43 protein, prevents lesion spread and reduces vascular permeability in preclinical models of central nervous system injury. The
Helen V Danesh-Meyer et al.
Brain : a journal of neurology, 135(Pt 2), 506-520 (2012-02-22)
Connexin43 gap junction protein is expressed in astrocytes and the vascular endothelium in the central nervous system. It is upregulated following central nervous system injury and is recognized as playing an important role in modulating the extent of damage. Studies
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