Sk052-145-2 is a potent and selective inhibitor of bacterial Lipoprotein signal peptidase (Lsp). Sk052-145-2 potently inhibits growth of E. Coli in a presence of polymyxin B nonapeptide (PMBN).
potent and selective inhibitor of bacterial Lipoprotein signal peptidase (Lsp)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Cell chemical biology, 25(3), 301-308 (2018-01-18)
As resistance to antibiotics increases, the exploration of new targets and strategies to combat pathogenic bacteria becomes more urgent. Ideal protein targets are required for viability across many species, are unique to prokaryotes to limit effects on the host, and have
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