SML1925
Bepristat 2a hydrochloride
≥95% (HPLC)
동의어(들):
6-Bromo-2-[[[2-(diethylamino)ethyl]amino]methyl]-5-hydroxy-1-phenyl-1H-indole-3-carboxylic acid ethyl ester hydrochloride
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
| 사이즈/SKU | 재고 정보 | 가격 (VAT 별도) |
|---|---|---|
5 mg | 예상 입고일2026년 10월 19일재고 수량 조회Seoul Warehouse South Korea | ₩169,201 |
25 mg | 예상 입고일2026년 10월 19일재고 수량 조회Seoul Warehouse South Korea | ₩680,862 |
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C24H30BrN3O3 · xHCl
CAS 번호:
Molecular Weight:
488.42 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
CCN(CC)CCNCC1=C(C(OCC)=O)C2=CC(O)=C(Br)C=C2N1C3=CC=CC=C3.[H]Cl
InChI key
HKOKWSVFJJFYDV-UHFFFAOYSA-N
Biochem/physiol Actions
Bepristat 2a is a selective reversible inhibitor of protein disulfide isomerase (PDI), an enzyme in the endoplasmic reticulum that catalyzes disulfide bond breakage and reformation to catalyze protein folding. Unlike most PDI inhibitors, Bepristat 2a binds at the substrate-binding site, rather than the catalytic site. Bepristat 2a blocked PDI activity with an IC50 value of 1200 nM, while enhancing catalytic activity of remote PDI domains. PDI is up-regulated in several cancers, has been implicated in neurodegenerative processes, and plays an important role in thrombus formation. Bepristat 2a potently inhibited platelet aggregation and thrombus formation in vivo.
Bepristat 2a is a selective reversible inhibitor of protein disulfide isomerase (PDI).
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이 품목 | |||
|---|---|---|---|
| description ≥95% (HPLC) | description >98% (TLC), powder | description ≥98% (HPLC) | description ≥98% (HPLC), solid |
| assay ≥95% (HPLC) | assay >98% (TLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form solid |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. - | storage temp. −20°C | storage temp. 2-8°C |
| solubility H2O: 10 mg/mL, clear | solubility - | solubility DMSO: 20 mg/mL, clear | solubility H2O: >5 mg/mL |
| storage condition desiccated | storage condition - | storage condition desiccated | storage condition - |
저장 등급
11 - Combustible Solids
무슨 일이 일어나고 있는 걸까?
WGK 3
인화점 (F)
Not applicable
인화점 (°C)
Not applicable