SML1626

TFCA

≥98% (HPLC)

• 동의어(들): 3-(3,4-Dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide, N-(4-Trifluoromethylphenyl) 3,4-dimethoxycinnamamide
• 실험식(Hill 표기법): C₁₈H₁₆F₃NO₃
• CAS Number: 895700-18-2
• Molecular Weight: 351.32
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825510
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 25 mg/mL, clear
• 저장 온도: room temp
• SMILES string: O=C(NC1=CC=C(C(F)(F)F)C=C1)/C=C/C2=CC=C(OC)C(OC)=C2
• InChI: 1S/C18H16F3NO3/c1-24-15-9-3-12(11-16(15)25-2)4-10-17(23)22-14-7-5-13(6-8-14)18(19,20)21/h3-11H,1-2H3,(H,22,23)/b10-4+
• InChI key: KFWWXJZNIMFFRO-ONNFQVAWSA-N

설명

생화학적/생리학적 작용

TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor.

TFCA is a Liver X receptor α (LXRα) antagonist.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable