SML1366
CVT-10216
≥98% (HPLC)
동의어(들):
3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]-benzoic acid, 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid, CVT 10216, GS 455534
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모든 사진(1)
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5 MG
₩249,792
25 MG
₩801,850
About This Item
실험식(Hill 표기법):
C24H19NO7S
CAS Number:
Molecular Weight:
465.48
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 10 mg/mL, clear
저장 온도
2-8°C
SMILES string
O=C(O)C1=CC(COC2=CC=C3C(OC=C(C4=CC=C(NS(C)(=O)=O)C=C4)C3=O)=C2)=CC=C1
InChI
1S/C24H19NO7S/c1-33(29,30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12,14,25H,13H2,1H3,(H,27,28)
InChI key
YYOOFJZTRCPVFD-UHFFFAOYSA-N
일반 설명
CVT-10216 is a 5-HT2c agonist.[1]
생화학적/생리학적 작용
CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2 (ALDH-2), thereby inhibiting dopamine synthesis. CVT-10216 is active in suppressing alcohol and cocaine use, and anxiety.
CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2.
CVT-10216 possesses unequivocal anxiolytic properties. It will not affect the suppression of locomotor activity by mCPP (m-chlorophenylpiperazine).[1]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Bin Yuan et al.
PloS one, 15(11), e0242809-e0242809 (2020-12-01)
The bone marrow microenvironment (BME) in acute myeloid leukemia (AML) consists of various cell types that support the growth of AML cells and protect them from chemotherapy. Mesenchymal stromal cells (MSCs) in the BME have been shown to contribute immensely
David H Overstreet et al.
Pharmacology, biochemistry, and behavior, 94(2), 255-261 (2009-09-15)
CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking. Anxiety plays a role in alcoholism. The present study asks whether CVT-10216 has anxiolytic properties, as reflected in social interaction behavior in four unrelated rodent models:
Simin Zhang et al.
Aesthetic plastic surgery, 44(3), 993-1005 (2020-01-19)
The cutaneous wound healing process mainly comprises re-epithelialization, fibrosis, and neovascularization. Impaired wound healing is common but tricky in plastic surgery. Aldehyde dehydrogenase 2 (ALDH2), the most effective subset of the ALDH enzyme family, is known to exert a major
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