SML1248

KT182

≥98% (HPLC)

• 동의어(들): [4-[3′-(Hydroxymethyl)[1,1′-biphenyl]-4-yl]-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone
• 실험식(Hill 표기법): C₂₇H₂₆N₄O₂
• CAS Number: 1402612-62-7
• Molecular Weight: 438.52
• MDL number: MFCD28118914
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825742
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: O=C(N1N=NC(C2=CC=C(C3=CC=CC(CO)=C3)C=C2)=C1)N4CCCCC4C5=CC=CC=C5
• InChI: 1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2
• InChI key: GICNKPZHUCVFNM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

KT182 is a very potent, orally bioavailable, selective inhibitor of ABHD6 (a/b-Hydrolase Domain Containing 6). IC₅₀ = 1.7 nM. KT182 inhibits ABHD6 activity in the brain and liverin mice (ip administration).

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H413
• 예방조치 성명서: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable