SML1216
Ravuconazole
≥97% (NMR)
동의어(들):
4-[2-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile, BMS-207147, ER-30346
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모든 사진(1)
크기 선택
보기 변경
5 MG
₩179,858
25 MG
₩721,665
About This Item
실험식(Hill 표기법):
C22H17F2N5OS
CAS Number:
Molecular Weight:
437.47
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥97% (NMR)
양식
powder
광학 활성
[α]/D -27 to -33°, c = 1 in methanol
색상
white to beige
solubility
DMSO: 20 mg/mL, clear
저장 온도
−20°C
SMILES string
Fc1c(ccc(c1)F)[C@](O)([C@@H](C)c3[s]cc(n3)c4ccc(cc4)C#N)C[n]2ncnc2
InChI
1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30,11-29-13-26-12-27-29)18-7-6-17(23)8-19(18)24/h2-8,10,12-14,30H,11H2,1H3/t14-,22+/m0/s1
InChI key
OPAHEYNNJWPQPX-RCDICMHDSA-N
생화학적/생리학적 작용
Ravuconazole (BMS-207147) is a potent and broad spectrum triazole antifungal. Ravuconazole is an inhibitor of sterol biosynthesis by inhibition of cytochrome P450 14α-demethylase, an enzyme in the sterol biosynthesis pathway that leads from lanosterol to ergosterol.
Ravuconazole is a potent and broad spectrum triazole antifungal.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Yara Almeida Machado et al.
Antimicrobial agents and chemotherapy, 64(8) (2020-05-20)
Mining existing agents that enhance the therapeutic potential of ergosterol biosynthesis inhibitors (EBI) is a promising approach to improve Chagas disease chemotherapy. In this study, we evaluated the effect of ravuconazole, an EBI, combined with amlodipine, a calcium channel blocker
Pollyanna Álvaro Spósito et al.
International journal of nanomedicine, 12, 3785-3799 (2017-05-30)
Self-emulsifying drug delivery systems (SEDDSs) are lipid-based anhydrous formulations composed of an isotropic mixture of oil, surfactant, and cosurfactants usually presented in gelatin capsules. Ravuconazole (Biopharmaceutics Classification System [BCS] Class II) is a poorly water-soluble drug, and a SEDDS type
활성 필터
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