SML0014

Scutellarin hydrate

≥98% (HPLC)

• 동의어(들): 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• 실험식(Hill 표기법): C₂₁H₁₈O₁₂ · xH₂O
• CAS Number: 27740-01-8
• Molecular Weight: 462.36 (anhydrous basis)
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: yellow
• solubility: DMSO: ≥10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O)O)Oc2cc3c(c(c2O)O)C(=O)C=C(O3)c4ccc(cc4)O
• InChI: 1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
• InChI key: DJSISFGPUUYILV-ZFORQUDYSA-N

설명

애플리케이션

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

생화학적/생리학적 작용

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

특징 및 장점

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable