SML0010

LY-334370 hydrochloride hydrate

≥98% (HPLC), powder

• 동의어(들): 4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride hydrate
• 실험식(Hill 표기법): C₂₁H₂₂FN₃O · HCl · xH₂O
• CAS Number: 199673-74-0
• Molecular Weight: 387.88 (anhydrous basis)
• MDL number: MFCD11519957
• UNSPSC 코드: 12352202
• PubChem Substance ID: 329825086
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to tan
• solubility: H₂O: ≥5 mg/mL (warmed)
• 주관자: Eli Lilly
• 저장 온도: 2-8°C
• SMILES string: Cl.CN1CCC(CC1)c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23
• InChI: 1S/C21H22FN3O.ClH/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15;/h2-7,12-14,23H,8-11H2,1H3,(H,24,26);1H
• InChI key: DGPDGAPZTPSHBL-UHFFFAOYSA-N

설명

애플리케이션

LY-334370 hydrochloride hydrate may be used to study 5-HT 1F-mediated cell signaling.

생화학적/생리학적 작용

LY-334370 hydrochloride is a selective 5-HT1F receptor agonist.

LY-334370 modulates the transmission in the mouse trigeminal system and inhibits the neuronal responses within rat Sp5C by inhibiting c-Fos activation. It shows efficacy in aborting migraine attacks.[1][2]

특징 및 장점

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable