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Merck
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주요 문서

SCP0169

Sigma-Aldrich

HIV-1 Tat Peptide

HIV-TAT (48-57)
1명의 제품 평가자(총 1명)가 샘플 제품을 받았거나 프로모션에 참여했습니다

≥95% (HPLC), lyophilized powder

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크기 선택

1 MG
₩317,797

₩317,797


구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요


크기 선택

보기 변경
1 MG
₩317,797

About This Item

실험식(Hill 표기법):
C65H124N34O13
Molecular Weight:
1589.90
UNSPSC 코드:
12352202
NACRES:
NA.32

₩317,797


구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요

제품명

HIV-TAT (48-57),

분석

≥95% (HPLC)

양식

lyophilized

구성

Peptide Content, ≥55%

저장 조건

protect from light

저장 온도

−20°C

Amino Acid Sequence

Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-NH2

일반 설명

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat), a regulatory protein is coded by the Tat gene of HIV-1. Tat is made up of two exons, highly conserved regions, and subtype-specific regions.[1]

생화학적/생리학적 작용

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat) participates in the pathogenesis of HIV-related complications. Tat protein is also involved in HIV-related cardiac dysfunction.[1] HIV-TAT (48-57) is used to facilitate the internalization of synthetic peptides.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yanan Jiang et al.
Journal of translational medicine, 16(1), 121-121 (2018-05-10)
The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which
S-M Lee et al.
Clinical and experimental immunology, 161(3), 504-511 (2010-07-22)
The immune receptor expressed on myeloid cells 1 (IREM-1) has been known to regulate the activities of myeloid cells through its immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its intracellular region. In order to investigate its effect on macrophage activation, a
S-M Lee et al.
Clinical and experimental immunology, 167(3), 438-446 (2012-02-01)
The immune receptor expressed on myeloid cells 1 (IREM-1/CD300F) has been shown to inhibit various inflammatory processes in myeloid cells, such as macrophages and mast cells. IREM-1 exerts its inhibitory effect through its intracellular immunoreceptor tyrosine-based inhibition motifs (ITIMs). In

질문

후기

1명의 제품 평가자(총 1명)가 샘플 제품을 받았거나 프로모션에 참여했습니다

활성 필터

    • 상품평 1
    • 투표 3
    별 5개 중 1개입니다.

    Purchase a different product

    Quite disappointed in this product. For one, they do not provide any information on reconstitution of this lyophilized powder, not even whether to use dH20 or not. Additionally, please look closely at the 3 cited papers that allegedly used this product. One is a review that didn't actually use the product, and the other two are from the same lab that published what looks to be the same experiment twice, but without sufficient methodology. They list that, "Fusion proteins containing ITIMs and HIV-TAT48–57 and its negative control containing only HIV-TAT48–57 were custom-designed and synthesized by Peptron Inc. (Daejeon, Korea)" which is not this product? Additionally, their only methodology in terms of use does not include reconstitution, merely this sentence hidden below a figure, "Cells were pre-treated with 5 µM of TAT, TAT–YADL, TAT–YVTM, TAT–YASL, TAT–YCNM or TAT–YSTI for 30 min before stimulation with 1 µg/ml of lipopolysaccharide (LPS) for 24 h."

    When I contacted a rep about my concerns they said they couldn't help with reconstitution instructions and I should have checked to see if they had instructions before purchasing.... a less than stellar response. Save yourself the time, money, and hassle and find a different product.

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    도움이 되었습니까?

    1. Sigma-Aldrich Corporation의 답변:

      Thank you for taking the time to leave a review. We are sorry to hear that your experience did not meet expectations. Our Technical Service team has reached out to you with additional resources in effort to resolve this issue. We apologize for any inconvenience this may have caused.

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