SAB5900406

Anti-Monkeypox virus/MPXV A35R Antibody (SAA0287)

• 동의어(들): A35R, Bifunctional EEV membrane phosphoglycoprotein, Bifunctional EEV membrane phosphoglycoprotein/associates with A36R, Bifunctional EEV membrane protein, EEV membrane phosphoglycoprotein, EEV membrane phosphoglycoprotein C-type,EEV membrane phosphoglycoprotein, C-type lectin-like domain, MPXV-COP-139, MPXV-SL-139, MPXV-WRAIR139, Monkeypox virus (MPXV)
• UNSPSC 코드: 12352203

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 재조합: expressed in CHO cells
• 결합: unconjugated
• 항체 형태: affinity purified immunoglobulin
• 클론: SAA0287, recombinant monoclonal
• 분석: >95% (SDS-PAGE)
• 양식: liquid
• 분자량: 150 kDa
• 종 반응성: monkeypox virus
• 농도: 1 mg/mL
• 기술: ELISA: 1:2000-1:4000; neutralization: 0.01-10 μg/mL
• 색상: colorless
• pH: 7.4
• 동형: IgG2a, kappa
• 단백질 ID 수납 번호: NP_536572.1
• UniProt 수납 번호: Q80KX2; Q8V4U4
• 배송 상태: wet ice
• 저장 온도: -65 to -96°C
• 타겟 번역 후 변형: unmodified

설명

일반 설명

Anti-Monkeypox virus /MPXV A35R Antibody, clone SAA0287 is a monoclonal antibody produced in mouse. It is a single, specific antibody produced from a single clone of B cells. It is composed of two heavy chains and two light chains linked by disulfide bonds. The two heavy chains are linked to each other by non-covalent bonds and the light chains are linked to the heavy chains by disulfide bonds.

Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

특이성

Monoclonal Anti-Monkeypox virus /MPXV A35R Antibody, clone SAA0287 binds to the viral antigen, specifically the A35R protein of the Monkeypox virus. This binding inhibits the virus from entering the host cell and prevents the virus from replicating.

애플리케이션

ELISA,neutralization

포장

100µg per vial / 1 mg per vial

저장 및 안정성

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable