SAB5801051

Alpaca Anti-Chicken IgY HRP single domain Antibody

recombinant Alpaca(VHH) Nano antibody

• 동의어(들): Recombinant Alpaca single variable domain secondary Nanobody
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: alpaca
• 재조합: expressed in E. coli
• 결합: horse radish peroxidase (HRP)
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: secondary antibodies
• 클론: recombinant monoclonal
• 양식: lyophilized solid
• 분자량: 14 kDa
• 종 반응성: chicken, Alpaca
• 기술: ELISA: 1:10000-1:50000; western blot: 1:10000-1:50000
• 크기: 0.1 mL
• 색상: colorless
• 동형: VHH
• 배송 상태: wet ice
• 저장 온도: 2-8°C

설명

일반 설명

Alpaca Anti-Chicken IgY HRP single domain Antibody is designed to specifically detect chicken IgY. It is a monovalent, single domain, recombinant antibody to chicken IgY coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Alpaca Anti-Chicken IgY HRP single domain Antibody detects the chicken IgY selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.

Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.

VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

특이성

Fc region of chicken IgY
Isotype: VHH domain of alpaca IgG2b/2c

면역원

Recombinant Alpaca single variable domain secondary nano antibody

포장

100 μg in Glass bottle

물리적 형태

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

재구성

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

저장 및 안정성

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Protect from light. Stable for 12 months at -20°C

기타 정보

No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317,H412
• 예방조치 성명서: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 3 - Skin Sens. 1
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable