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Merck
모든 사진(2)

주요 문서

SAB5201735

Sigma-Aldrich

Monoclonal Anti-Tcp1 Alpha - Atto 390 antibody produced in rat

clone 23c, purified immunoglobulin

동의어(들):

Anti-AI528772, Anti-Ccta, Anti-Tric, Anti-p63

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rat

Quality Level

결합

Atto 390 conjugate

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

23c, monoclonal

양식

buffered aqueous solution

분자량

antigen predicted mol wt 60 kDa

종 반응성

mouse, human, dog, rabbit, rat, hamster, bovine, sheep

농도

1 mg/mL

기술

immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG2c

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Tcp1(21454)

일반 설명

Tcp1 (t-complex protein ) is a chaperonin and a ATPase complex that encodes a chaperonin, localized to the cytosol.

면역원

Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli. Detects the COOH group.

생화학적/생리학적 작용

Tcp1 (t-complex protein) is involved in protein folding mechanism of essential proteins such as actins, tubulin, cyclin E, α-transducin and von Hippel Lindau protein. Tcp1 participates in synthesis of proteins that make up the cytoskeleton and thus involved in cellular processes such as chromosome segregation, cell migration, and intracellular transport. Increased TCP1 gene expression is observed in cancer and upregulation elevates with the disease progression.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

PBS pH7.4, 50% glycerol, 0.1% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis.
Jiang X, et al.
Oncotarget, 6(39), 42105-42105 (2015)
The molecular chaperone CCT modulates the activity of the actin filament severing and capping protein gelsolin in vitro.
Svanstrom A and Grantham J
Cell Stress & Chaperones, 21(1), 55-62 (2016)
TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington?s disease.
Zhao X, et al.
Proceedings of the National Academy of Sciences of the USA, 113(38), E5655-E5664 (2016)
Satyabrata Sinha et al.
Investigative ophthalmology & visual science, 55(6), 3775-3785 (2014-05-24)
While some evidence suggests an essential role for the chaperonin containing t-complex protein 1 (CCT) in ciliogenesis, this function remains poorly understood mechanistically. We used transgenic mice, previously generated in our lab, and characterized by a genetically-induced suppression of CCT

질문

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