The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.
면역원
Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1
생화학적/생리학적 작용
The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.
특징 및 장점
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물리적 형태
PBS pH7.4, 50% glycerol, 0.09% sodium azide
면책조항
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
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