SAB5200898
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse
clone S327-95, purified immunoglobulin
동의어(들):
Anti-GRIN2A, Anti-HNR2A, Anti-NMDA 2A
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩706,034
₩706,034
예상 입고일2025년 7월 10일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(3)
크기 선택
보기 변경
100 μG
₩706,034
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩706,034
예상 입고일2025년 7월 10일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
mouse
Quality Level
결합
Allophycocyanin conjugate
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
S327-95, monoclonal
양식
buffered aqueous solution
분자량
antigen predicted mol wt 170 kDa
종 반응성
human, rat, mouse
농도
1 mg/mL
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
동형
IgG2a
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
rat ... Grin2a(24409)
일반 설명
The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is mapped to human chromosome 16p13.2. It codes for a transmembrane ligand-gated ion channel called N-methyl-D-aspartate glutamate receptor α2 subunit.
면역원
Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A
생화학적/생리학적 작용
The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is associated with focal epilepsy and impaired speech. NMDA glutamate receptor α2 subunit is involved in neuron development, maintains synaptic plasticity and is associated with memory. GRIN2A is related to schizophrenia and Alzheimer′s disease. Mutations in GRIN2A gene upregulates NMDA action and might lead to melanoma tumors. NMDA participates in apoptosis and proliferation of cancer cells.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
PBS pH7.4, 50% glycerol, 0.09% sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
GRIN2A mutations in epilepsy-aphasia spectrum disorders
Yang X, et al.
Brain & Development, 40(3), 205-210 (2018)
2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor
Gorska PM, et al.
Journal of Cellular Physiology, 232(11), 3030-3049 (2017)
Epilepsy in patients with GRIN2A alterations: genetics, neurodevelopment, epileptic phenotype and response to anticonvulsive drugs
von Stupnagel C, et al.
European Journal of Paediatric Neurology, 21(3), 530-541 (2017)
Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency-molecular profiling and functional rescue
Addis L, et al.
Scientific Reports, 7(1), 66-66 (2017)
Selected GRIN2A mutations in melanoma cause oncogenic effects that can be modulated by extracellular glutamate
Dmello SAN, et al.
Cell Calcium, 60(6), 384-395 (2016)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
