SAB4702105

Monoclonal Anti-CD200 PE produced in mouse

• 동의어(들): MOX, MRC, OX-2
• UNSPSC 코드: 12352203

속성

• 결합: phycoerythrin (R-PE) conjugate
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: OX-104, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 기술: flow cytometry: suitable
• 동형: IgG1κ
• UniProt 수납 번호: P41217
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CD200(4345)

설명

일반 설명

CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.

특이성

The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.

면역원

recombinant human CD200

물리적 형태

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

제조 메모

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

저장 및 안정성

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

기타 정보

The antibody solution should be gently mixed before use.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable