SAB4702004

Monoclonal Anti-NG2 PE produced in mouse

• 동의어(들): CSPG4, Chondroitin sulfate proteoglycan 4, MCSP, MSK16
• UNSPSC 코드: 12352203

속성

• 결합: phycoerythrin (R-PE) conjugate
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: 7.1, monoclonal
• 형태: buffered aqueous solution
• 종 반응성: human
• 기술: flow cytometry: suitable
• 동형: IgG1
• UniProt 수납 번호: Q6UVK1
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CSPG4(1464)

설명

일반 설명

NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

특이성

The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

면역원

Human bone marrow stromal cells infected with SV-40

물리적 형태

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

제조 메모

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

저장 및 안정성

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

기타 정보

The antibody solution should be gently mixed before use.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable