₩677,107
예상 입고일2025년 8월 08일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 67 kDa
종 반응성
human, rat, mouse
농도
~1 mg/mL
기술
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pThr184)
유전자 정보
human ... MAP3K7(6885)
일반 설명
Transforming growth factor β (TGF-β)-activated kinase 1 (TAK1) is encoded by MAP3K7. TAK1 is a 606-residue protein, that contains a serine-threonine/tyrosine-protein kinase catalytic domain and a C-terminal coiled-coil domain. It is a member of the mitogen-activated protein kinase kinase kinase family (MAP3K). This gene is mapped to human chromosome 6q15.
면역원
The antiserum was produced against synthesized peptide derived from human TAK1 around the phosphorylation site of Thr184.
Immunogen Range: 161-210
Immunogen Range: 161-210
생화학적/생리학적 작용
Transforming growth factor β (TGF-β)-activated kinase 1 (TAK1) participates in the mitogen-activated protein kinase (MAPK)-p38 signaling pathway. This gene also participates in the autophagy process in retinal pigment epithelial cells. Mutations in MAP3K7 result in cardiospondylocarpofacial syndrome.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
?III-tubulin overexpression is an independent predictor of prostate cancer progression tightly linked to ERG fusion status and PTEN deletion
Tsourlakis MC, et al.
The American Journal of Pathology, 184(3), 609-617 (2014)
TAK1 is involved in the autophagy process in retinal pigment epithelial cells.
Green YA
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 94(2), 188-196 (2016)
Heterozygous Mutations in MAP3K7, Encoding TGF-?-Activated Kinase 1, Cause Cardiospondylocarpofacial Syndrome.
Le Goff C
American Journal of Human Genetics, 99(2), 407-413 (2016)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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