SAB4503558
Anti-RABEP1 antibody produced in rabbit
affinity isolated antibody
동의어(들):
Rabaptin-4, Rabaptin-5, Rabaptin-5α, Renal carcinoma antigen NY-REN-17
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩597,429
₩597,429
예상 입고일2025년 7월 14일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
100 μG
₩597,429
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩597,429
예상 입고일2025년 7월 14일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 99 kDa
종 반응성
human, rat, mouse
농도
~1 mg/mL
기술
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... RABEP1(9135)
일반 설명
Anti-RABEP1 Antibody detects endogenous levels of total RABEP1 protein.
The gene RABEP1 (Rab GTPase-binding effector protein 1) is mapped to human chromosome 17p13.2. The encoded protein has two Rab5-binding sites.
The gene RABEP1 (Rab GTPase-binding effector protein 1) is mapped to human chromosome 17p13.2. The encoded protein has two Rab5-binding sites.
면역원
The antiserum was produced against synthesized peptide derived from human RABEP1.
Immunogen Range: 549-598
Immunogen Range: 549-598
생화학적/생리학적 작용
RABEP1 (Rab GTPase-binding effector protein 1) is an effector of Rab5 and plays an important role in homotypic and heterotypic fusions of early endosomes. Absence of RABEP1 suppresses Rab5-associated early endosome fusion.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
PDGFRB-rearranged T-lymphoblastic leukemia/lymphoma occurring with myeloid neoplasms: the missing link supporting a stem cell origin.
Sarah L Ondrejka et al.
Haematologica, 99(9), e148-e151 (2014-06-22)
Zhe Zhang et al.
eLife, 3, doi:10-doi:10 (2014-06-25)
Rabex-5 and Rabaptin-5 function together to activate Rab5 and further promote early endosomal fusion in endocytosis. The Rabex-5 GEF activity is autoinhibited by the Rabex-5 CC domain (Rabex-5CC) and activated by the Rabaptin-5 C2-1 domain (Rabaptin-5C21) with yet unknown mechanism.
Mi Hee Park et al.
Experimental & molecular medicine, 47, e200-e200 (2015-12-19)
Endocytosis is differentially regulated by hypoxia-inducible factor-1α (HIF-1α) and phospholipase D (PLD). However, the relationship between HIF-1α and PLD in endocytosis is unknown. HIF-1α is degraded through the prolyl hydroxylase (PHD)/von Hippel-Lindau (VHL) ubiquitination pathway in an oxygen-dependent manner. Here
활성 필터
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