SAB4502369
Anti-HDAC8 antibody produced in rabbit
affinity isolated antibody
동의어(들):
FKSG78, G-protein coupled receptor 95, GPR87, GPR95, Probable G-protein coupled receptor 87
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩597,429
₩597,429
예상 입고일2025년 6월 10일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(2)
크기 선택
보기 변경
100 μG
₩597,429
About This Item
₩597,429
예상 입고일2025년 6월 10일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 41 kDa
종 반응성
human, rat, mouse
농도
~1 mg/mL
기술
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... HDAC8(55869)
일반 설명
Anti-HDAC8 Antibody detects endogenous levels of total HDAC8 protein.
The HDAC8 (histone deacetylase 8) gene is mapped to human chromosome Xq13.1. The encoded protein belongs to the class 1 histone deacetylase family.
면역원
The antiserum was produced against synthesized peptide derived from human HDAC8.
Immunogen Range: 5-54
Immunogen Range: 5-54
생화학적/생리학적 작용
The HDAC8 (histone deacetylase 8) protein is significantly involved in cartilage development and matrix-specific gene transcription by catalyzing histone acetylation. HDAC8 has Zn2+-dependent hydrolase activity that deacetylates the acetyl lysine residues of both histone and non-histone proteins. Deacetylation of structural maintenance of chromosome protein 3(SMC3) by HDAC8 is necessary for recycling of cohesin complex during cell cycle. Mutation in the gene is observed in Cornelia de Lange syndrome which is characterised by mental retardation and facial deformity.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Cloning and characterization of human histone deacetylase 8.
Van den Wyngaert I
Febs Letters, 478(1-2), 77-83 (2000)
Structure-Based Identification of HDAC8 Non-histone Substrates.
Alam N
Structure, 24(3), 458-468 (2016)
Structural aspects of HDAC8 mechanism and dysfunction in Cornelia de Lange syndrome spectrum disorders.
Deardorff MA
Protein Science, 25(11), 1965-1976 (2016)
Bo Du et al.
The Kaohsiung journal of medical sciences, 36(11), 904-910 (2020-07-10)
Alcoholic hepatitis (AH) is identified as an inflammatory syndrome with high morbidity and mortality as a result of severe hepatocellular dysfunction and liver injury. Accumulated studies indicated that miRNAs are involved in AH. The potential effect of miR-451a in AH
MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation.
Chen W
Biochimica et Biophysica Acta, 1863(12), 2881-2891 (2016)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
