Anti-LY6E Antibody detects endogenous levels of total LY6E protein.
Anti-LY6E Antibody detects endogenous levels of total LY6E protein. LY6E (lymphocyte antigen 6 family member E) is a glycosylphosphatidylinositol-anchored, interferon (IFN)-inducible protein, that is located on human chromosome 8q24. It is also called as RIG-E.
면역원
The antiserum was produced against synthesized peptide derived from human LY6E.
Immunogen Range: 17-66
생화학적/생리학적 작용
LY6E (lymphocyte antigen 6 family member E) controls T lymphocytes proliferation, differentiation and development. It induces HIV-1 Infection. Overexpression of LY6E gene in the peripheral blood cells of individuals with SLE (systemic lupus erythematosus) is associated with lupus activity.
특징 및 장점
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.
J Tang, et al.
Lupus, 17(9), 805-813 (2008)
Interferon-inducible LY6E Protein Promotes HIV-1 Infection.
Yu J, et al.
Journal of Biochemistry, 292(11), 4674-4685 (2017)
RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.
M Mao, et al.
Proceedings of the National Academy of Sciences of the USA, 93(12), 5910-5914 (1996)
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