Anti-Prostate-specific Antigen Antibody detects endogenous levels of total Prostate-specific Antigen protein.
The prostate-specific antigen (PSA) is coded by KLK3 (kallikrein 3) gene. It is located on human chromosome 19q13.33.
면역원
The antiserum was produced against synthesized peptide derived from human Prostate-specific Antigen.
Immunogen Range: 81-130
생화학적/생리학적 작용
The prostate-specific antigen (PSA) plays a major role in sperm motility. It participates in tumor invasion and metastasis. It also plays a major role in the etiology of prostate cancer (PCa).
특징 및 장점
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Single-nucleotide polymorphism rs1058205 of KLK3 is associated with the risk of prostate cancer: A case-control study of Han Chinese men in Northeast China.
Molecular medicine reports, 17(6), 8203-8211 (2018-04-17)
The androgen receptor (AR) has a crucial role in prostate cancer. RNA‑binding protein‑mediated post‑transcriptional regulation is important in the initiation and development of cancer. The present study attempted to elucidate the mutual association of AR and RNA‑binding protein quaking (QKI)
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