Anti-GFAP Antibody detects endogenous levels of total GFAP protein.
Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system). It is located on human chromosome 17q21.
면역원
The antiserum was produced against synthesized peptide derived from human GFAP.
Immunogen Range: 11-60
애플리케이션
Anti-GFAP, N-Terminal antibody has been used in immunocytochemical analysis , confocal and fluorescent microscopic imaging , immunostaining and western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper)
생화학적/생리학적 작용
Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions.It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.
특징 및 장점
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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GFAP promoter directs astrocyte-specific expression in transgenic mice
Brenner M, et al.
The Journal of Neuroscience (1994)
MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
Tseng KY, et al.
Molecular Therapy (2017)
Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice
Peng S, et al.
Annals of Clinical and Translational Neurology, 2, 1085-1104 (2015)